"Prime Factors" is the tenth episode of Star Trek: Voyager. This television episode is a science fiction story, set in the 24th century of the Star Trek universe about a spacecraft stranded on the other side of the Galaxy that must make its way back to Earth. The ship is led by Captain Kathryn Janeway who must manage a ragtag crew of Starfleet, Maquis, and aliens; the show aired on UPN between 1995 and 2001.

This teleplay was written by Greg Elliot and Michael Perricone, from a story written by David R. George III and Eric A. Stillwell, and directed by Les Landau. It was broadcast on television on March 20, 1995.

Voyager picks up a distress call and makes contact with a new world and its inhabitants. In addition to major scenes with cast regulars such as Captain Janeway and Ensign Harry Kim, the crew encounters a variety of aliens with Ronald Guttman as Gath, Yvonne Suhor as Eudana, and Andrew Hill Newman as Jaret. Voyager's crew including Martha Hackett as Seska and Josh Clark as Lieutenant Joe Carey also have some screentime.